Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis

Not yet recruitingOBSERVATIONAL
Enrollment

7,838

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Septic ShockFluid Resuscitation
Interventions
OTHER

Vasopressors

A haemodynamic resuscitation strategy based upon the restriction of IV fluids (by either volume or rate of infusion) with initiation or change of rate of vasopressors if required to meet perfusion targets

OTHER

Fluids

A strategy of resuscitation with intravenous fluids as the primary intervention to achieve perfusion targets with subsequent initiation or change of rate of vasopressors if required.

All Listed Sponsors
lead

Australian and New Zealand Intensive Care Research Centre

OTHER

NCT05453565 - Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis | Biotech Hunter | Biotech Hunter