Circadian Influence on Prolonged Exposure Therapy for PTSD

NAActive, not recruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

July 1, 2022

Primary Completion Date

August 15, 2025

Study Completion Date

August 15, 2025

Conditions
PTSD
Interventions
BEHAVIORAL

Prolonged Exposure Therapy for Posttraumatic Stress Disorder

Manualized procedures deliver ten 90-minute sessions targeted to occur weekly and administered via tele-health with the same study therapist. Session 1 will focus on psychoeducation. Session 2 involves construction of the in vivo exposure hierarchy. Sessions 3-10 focus on in-session imaginal exposures to the worst trauma memory for 45-60 min followed by 15-20 min of processing the imaginal exposure. For homework, participants will be instructed to confront situations on their hierarchy on a daily basis using recording of their imaginal exposure. Subjective Units of Distress (SUDS) ratings will be taken throughout imaginal exposure exercises.

Trial Locations (1)

02130-4817

VA Boston Healthcare System, Boston

All Listed Sponsors
collaborator

VA Boston Healthcare System

FED

collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Massachusetts General Hospital

OTHER