Plasma Exchange Therapy for Post- COVID-19 Condition: A Pilot, Randomized Double-Blind Study

PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 22, 2022

Primary Completion Date

June 6, 2023

Study Completion Date

June 6, 2023

Conditions
Post-COVID19 Condition
Interventions
COMBINATION_PRODUCT

Plasma Exchange Procedure

Plasma exchanges will be performed with 5% albumin as the replacement fluid. The typical schedule prescribed will be an exchange of 1 volemia. Blood will be separated into cells and plasma; the cells will be combined with reconstituted 5% human serum albumin and reinfused into the patient with normal saline

OTHER

Sham Plasma Exchange Procedure

For sham plasma exchange procedures, a sound behind the curtain will be performed imitating the sound of the cell processing platform. In these cases, only one infusion of 200 to 250ml of sterile saline solution 0.9% will be performed during the time stablished for all procedures. Albumin will not be necessary for those patients in the Sham plasma exchange arm

Trial Locations (1)

08916

Germans Trias i Pujol Hospital, Badalona

All Listed Sponsors
collaborator

IrsiCaixa

OTHER

collaborator

Banc de Sang i Teixits

OTHER

lead

Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia

OTHER