A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Columbia University Medical Center, New York

New York Medical College, Valhalla

Long Island Jewish Medical Center, New Hyde Park

Albany Medical College, Pulmonary and Critical Care Medicine, Albany

SUNY Upstate Medical University, Syracuse

CF Therapeutics Development Center of Western New York, Buffalo

UPMC Children's Hospital of Pittsburgh, Pittsburgh

Children's Hospital of Philadelphia, Philadelphia

University of Virginia Health System, Charlottesville

West Virginia University, Morgantown

Wake Forest Baptist Health, Winston-Salem

Atrium Health Levine Children's Hospital, Charlotte

Prisma Health Richland Campus, Columbia

The Emory Clinic at Chantilly, Atlanta

Augusta University, Augusta

Nemours Children's Specialty Care, Pensacola

University of Florida, Shands Hospital, Gainesville

Central Florida Pulmonary Group,PA, Orlando

Joe DiMaggio Cystic Fibrosis & Pulmonary Center, Hollywood

University of Miami Miller School of Medicine, Miami

Johns Hopkins All Children's Hospital Outpatient Care Center, St. Petersburg

University of Alabama at Birmingham, Birmingham

Vanderbilt University Medical Center, Nephrology Clinical Trials Center, Nashville

University of Tennessee Medical Center, Knoxville

University of Kentucky, Lexington

Nationwide Children's Hospital, Columbus

ProMedica Toledo Hospital/Toledo Children's Hospital/Pediatric Pulmonary & Cystic Fibrosis Center, Toledo

Akron Children's Hospital, Akron

Dayton Children's Hospital, Dayton

Indiana University, Indianapolis

Riley Hospital for Children at Indiana University Health, Indianapolis

Michigan Medicine, Ann Arbor

Harper University Hospital, Detroit

Spectrum Health Medical Group Adult Cystic Fibrosis Care Center, Grand Rapids

University Hospital and UW Health Clinics, Madison

University of Minnesota, Minneapolis

Sanford Children's Speciality Clinic, Sioux Falls

Billings Clinic, Billings

Northwestern Memorial Hospital, Chicago

Cardinal Glennon Children's Hospital - St. Louis University, St Louis

Washington University School of Medicine / St. Louis Children's Hospital, St Louis

The Children's Mercy Hospital, Kansas City

Childrens Hospital University of Missouri Health Sciences Center, Columbia

University of Kansas Medical Center, Kansas City

Nebraska Medical Center, Omaha

Tulane Medical Center, New Orleans

University of Arkansas for Medical Sciences, Little Rock

University of Oklahoma Health Sciences Center, Oklahoma City

Santiago Reyes, M.D., Oklahoma City

The University of Texas Southwestern Medical Center, Dallas

Cook Children's Health Care System, Fort Worth

Texas Children's Hospital - Baylor College of Medicine, Houston

Children's Hospital of Colorado, Aurora

National Jewish Health, Denver

St. Luke's Cystic Fibrosis Center of Idaho, Boise

University of Utah, Salt Lake City

Banner University of Arizona Medical Center, Tucson

Children's Hospital Los Angeles, Los Angeles

Miller Children's Hospital / Long Beach Memorial, Long Beach

University of California San Francisco, Lung Transplant Program, San Francisco

Kaiser Permanente, Oakland

University of California Davis Medical Center, Sacramento

Oregon Health & Science University, Portland

University of Washington Medical Center, Seattle

Providence Pediatric Pulmonary & Cystic Fibrosis Clinic, Spokane

Maine Medical Partners, Portland

Massachusetts General Hospital Cystic Fibrosis Center Clinical Research Center, Boston

Boston Children's Hospital, Boston

UMass Memorial Medical Center, Worcester

Dartmouth Hitchcock, Manchester

Morristown Medical Center, Morristown

Vermont Lung Center, Colchester

Royal Prince Alfred Hospital, Camperdown

The Prince Charles Hospital, Chermside

Alfred Hospital, Melbourne

Institute for Respiratory Health, Nedlands

Telethon Kids Institute, Nedlands

The Royal Children's Hospital, Parkville

Mater Adult Hospital, South Brisbane

Queensland Children's Hospital, South Brisbane

Westmead Hospital, Westmead

University of Graz, Graz

Medizinische Universität Innsbruck, Innsbruck

Uniklinikum Salzburg - Universitätsklinik für Pneumologie/Lungenheilkunde, Salzburg

Medizinische Universität Wien, Vienna

Cliniques Universitaires de Bruxelles Hopital Erasme, Brussels

Universitair Ziekenhuis Brussel - Campus Jette, Brussels

Universitair Ziekenhuis Gent, Ghent

Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg, Leuven

Cliniques Universitaires Saint-Luc, Woluwe-Saint-Lambert

University of Calgary Medical Clinic of the Foothills Medical Centre, Calgary

Stollery Children's Hospital, Edmonton

St. Joseph's Health Care London, London

Centre Hospitalier de l'Universite de Montreal (CHUM) Hotel-Dieu, Montreal

McGill University Health Centre, Glen Site, Montreal Children's Hospital, Montreal

Institut Universitaire de Cardiologie et Pneumologie de Quebec - Universite Laval, Québec

British Columbia Children's Hospital, Vancouver

St. Paul's Hospital, Vancouver

Klinika Detskych Infekcnich Nemoci, Brno

Fakultni nemocnice v Motole, Prague

Aarhus University Hospital, Aarhus

Juliane Marie Center, Rigshospitalet, Copenhagen

Groupe Hospitaler Pellegrin, CHU De Bordeaux, Bordeaux

CHU Lyon - Hopital Femme Mere-Enfant, Bron

Centre Hospitalier Intercommunal Creteil, Créteil

Institut Cœur Poumon, CHU de Lille, Lille

Hopital Arnaud de Villeneuve, Montpellier

Centre Hospitalier Universitaire (CHU) de Nice - Hopital Pasteur, Nice

Hopital Cochin, Paris

Hopital Robert Debre, Paris

Centre Hospitalier Lyon Sud, Pierre-Bénite

Centre de Perharidy, Roscoff

CHU de Rouen - Hopital Charles Nicolle, Rouen

Hôpital de Hautepierre, AX5, Strasbourg

Hopital Foch (Suresnes), Hopital Foch, Adultes, Suresnes

Hopital Bretonneau, Tours

Charite Paediatric Pulmonology Department, Berlin

Friedrich-Alexander University of Erlangen-Nuremberg, University Children's Hospital, Erlangen

Kinderklinik III, Abt. fur Pneumologie, Essen

Ruhrlandklinik Westdeutsches Lungenzentrum am Klinikum Essen, Essen

Johann Wolfgang Goethe University, Frankfurt

Justus-Liebig-Universität Gießen Zentrum für Kinderheilkunde und Jugendmedizin, Giessen

Hannover Medical School, Hanover

Medizinische Hochschule Hannover, Hanover

Mukoviszidose-Zentrum am Universitätsklinikum Jena, Klinik für Kinder- und Jugendmedizin, Jena

Johannes Gutenberg-Universitaet, Mainz

Pneumologisches Studienzentrum Muenchen-West, München

Klinikum Westbrandenburg (CF), Potsdam

Universitätsklinikum Ulm, Klinik für Kinder- und Jugendmedizin (CF), Ulm

Universitätsklinikum Würzburg, Würzburg

"General Hospital of Thessaloniki Papanikolaou", Thessaloniki

General Hospital of Thessaloniki 'Hippokratio', 3rd Pediatrics Department of Aristotle University of Thessaloniki, Thessaloniki

National Koranyi Institute for TBC and Pulmonology, Budapest

Pulmonology Institute Torokbalint, Törökbálint

Cork University Hospital, Cork

Children's Health Ireland at Crumlin, Dublin

Children's Health Ireland at Temple Street, Dublin

St. Vincent's University Hospital, Dublin

University Hospital Limerick (Pediatrics), Limerick

Hadassah Medical Organization, Jerusalem

Schneider Children's Medical Center of Israel, Petach Tikvah

Sheba Medical Center - The Edmond and Lili Safra Children's Hospital, Tel Litwinsky

Azienda Ospedaliero Universitaria Ospedale Riuniti, Ancona

Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer, Florence

IRCCS Istituto Giannina Gaslini-Ospedale Pediatrico, Genova

Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan

Malattie Apparato Respiratorio 2 - Centro Fibrosi Cistica, Orbassano

Centro Regionale Fibrosi Cistica, A.O. Ospedale San Carlo, Potenza

Azienda Ospedaliera di Verona - Ospedale Civile Maggiore, Verona

Academisch Medisch Centrum (Academic Medical Centre), Amsterdam

UMC St. Radboud, Nijmegen

Erasmus Medical Center, Rotterdam

HagaZiekenhuis van den Haag, The Hague

University Medical Center, Utrecht, Department of Pulmonology and Tuberculosis, Utrecht

Canterbury District Health Board, Christchurch

Starship Children's Hospital, Grafton

Waikato Hospital, Hamilton

Greenlane Clinical Centre, One Tree Hill

Haukeland Universitetssjukehus (CF), Bergen

Oslo University Hospital, Department of Paediatric Medicine, Oslo

Pediatric Hospital Polanki named of Maciej Płażyński, Gdansk

Klinika Mukowiscydozy IMD Oddozial Chorob Pluc Szpzoz IM. Dzieci WarszaWY, Łomianki

Hospital de Santa Maria, Lisbon

CHP - Hospital de Santo Antonio, Porto

Hospital Sao Joao, Porto

Hospital Saint Joan de Deu, Barcelona

Hospital Universitari Vall d'Hebron, Barcelona

Hospital Universitario 12 de Octubre, Madrid

Hospital Universitario Ramon y Cajal, Madrid

Hospital Virgen de la Arrixaca, Murcia

Corporacio Sanitaria Parc Tauli - Sabadell Hospital Universitari, Sabadell

Hospital Universitario Virgen del Rocio, Seville

Hospital Universitario y Politecnico La Fe, Valencia

Sahlgrenska Universitetssjukhuset, Gothenburg

Lund University Skanes Universitetssjukhus, Lund

Karolinska Universitetssjukhuset, Huddinge, Stockholm

Kinderspital Zuerich, Zurich

Birmingham Heartlands Hospital, Birmingham

University Hospitals Bristol and Weston NHS Foundation Trust, Bristol Royal Hospital, Bristol

Royal Papworth Hospital NHS Foundation Trust, Cambridge

Western General Hospital, Edinburgh

Royal Devon University Healthcare NHS Foundation Trust, Exeter

Clinical Research Facility, Queen Elizabeth University Hospital, Glasgow

Leeds General Infirmary, Leeds

St. James University Hospital, Leeds

Liverpool Heart and Chest Hospital, Liverpool

King's College Hospital, London

Royal Brompton Hospital, London

St. Bartholomew's Hospital, London

Royal Manchester Children's Hospital, Manchester

Wythenshawe Hospital, Manchester

Clinical Research Facility, Newcastle upon Tyne

All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Penarth

Southampton General Hospital, Southampton