NCT05443425View on ClinicalTrials.gov

Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

June 16, 2023

Primary Completion Date

January 5, 2027

Study Completion Date

January 5, 2027

Conditions
Acute Graft Versus Host DiseaseHematopoietic and Lymphoid System Neoplasm
Interventions
DRUG

Cholestyramine

Given PO

DRUG

Leflunomide

Given PO

DRUG

Steroid Therapy

Given steroid therapy

Trial Locations (1)

91010

RECRUITING

City of Hope Medical Center, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER