Palliative RadIotherapy of Multiple Metastatic Sites Before First Line of Systemic Therapy with Immune Checkpoint Inhibitors and Chemotherapy in Metastatic Non-Small-Cell Lung Cancer

Palliative irradiation of 2 to 5 sites (metastatic sites or/and primary lung tumour) in one week before systemic therapy. Systemic therapy should be given as soon as possible after irradiation.

Systemic therapy according to national/European recommendations.