Modulating Exercise Dosage to Improve Concussion Recovery

PHASE2RecruitingINTERVENTIONAL
Enrollment

216

Participants

Timeline

Start Date

August 5, 2022

Primary Completion Date

February 1, 2027

Study Completion Date

February 1, 2027

Conditions
Concussion, BrainTreatmentAerobic ExerciseInflammationDepression, Anxiety
Interventions
BEHAVIORAL

High Dose Exercise

The investigators will initially test and randomize adolescents ages 13-18 years old ≤14 days post-concussion to high dose aerobic exercise (\>150 min/week, individualized intensity level) or standard-of-care (symptom limited, self-guided physical activity), and re-test upon symptom resolution and 8-weeks post symptom resolution

Trial Locations (3)

80045

RECRUITING

University of Colorado Denver, Aurora

02115

RECRUITING

Boston Children's Hospital, Boston

02138

RECRUITING

Spaulding Rehabilitation Hospital, Cambridge

All Listed Sponsors
collaborator

Boston Children's Hospital

OTHER

collaborator

Spaulding Rehabilitation Hospital

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of Colorado, Denver

OTHER