190
Participants
Start Date
March 30, 2023
Primary Completion Date
March 9, 2030
Study Completion Date
March 9, 2030
Biospecimen Collection
Undergo collection of blood samples
Bone Scan
Undergo bone scan
Computed Tomography
Undergo CT scan
Magnetic Resonance Imaging
Undergo MRI
Multigated Acquisition Scan
Undergo MUGA
Olaparib
Given PO
Pazopanib
Given PO
Temozolomide
Given PO
Trabectedin
Given IV
Transthoracic Echocardiography Test
Undergo TTE
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Westchester, Harrison
Northwell Health/Center for Advanced Medicine, Lake Success
Memorial Sloan Kettering Nassau, Uniondale
Memorial Sloan Kettering Commack, Commack
Roswell Park Cancer Institute, Buffalo
Asplundh Cancer Pavilion, Willow Grove
Thomas Jefferson University Hospital, Philadelphia
Fox Chase Cancer Center, Philadelphia
MedStar Washington Hospital Center, Washington D.C.
VCU Massey Cancer Center at Stony Point, Richmond
VCU Massey Comprehensive Cancer Center, Richmond
West Virginia University Charleston Division, Charleston
UNC Lineberger Comprehensive Cancer Center, Chapel Hill
Duke University Medical Center, Durham
ECU Health Medical Center, Greenville
Medical University of South Carolina, Charleston
Saint Joseph's/Candler - Bluffton Campus, Bluffton
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
UM Sylvester Comprehensive Cancer Center at Plantation, Plantation
UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
University of Alabama at Birmingham Cancer Center, Birmingham
Vanderbilt University/Ingram Cancer Center, Nashville
Baptist Health Lexington, Lexington
UH Seidman Cancer Center at UH Avon Health Center, Avon
Case Western Reserve University, Cleveland
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland
UHHS-Chagrin Highlands Medical Center, Beachwood
Hillcrest Hospital Cancer Center, Mayfield Heights
Cleveland Clinic Foundation, Cleveland
University of Michigan Comprehensive Cancer Center, Ann Arbor
Bronson Methodist Hospital, Kalamazoo
West Michigan Cancer Center, Kalamazoo
Beacon Kalamazoo Cancer Center, Kalamazoo
Bronson Battle Creek, Battle Creek
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph
Trinity Health Muskegon Hospital, Muskegon
Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores
Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
Trinity Health Grand Rapids Hospital, Grand Rapids
University of Michigan Health - West, Wyoming
Corewell Health Reed City Hospital, Reed City
Munson Medical Center, Traverse City
Mary Greeley Medical Center, Ames
McFarland Clinic - Ames, Ames
McFarland Clinic - Boone, Boone
McFarland Clinic - Jefferson, Jefferson
McFarland Clinic - Marshalltown, Marshalltown
Mercy Medical Center - Des Moines, Des Moines
McFarland Clinic - Trinity Cancer Center, Fort Dodge
Heartland Oncology and Hematology LLP, Council Bluffs
University of Iowa/Holden Comprehensive Cancer Center, Iowa City
Medical College of Wisconsin, Milwaukee
Marshfield Medical Center-Marshfield, Marshfield
Marshfield Medical Center - Weston, Weston
Marshfield Medical Center-River Region at Stevens Point, Stevens Point
Marshfield Medical Center - Minocqua, Minocqua
Marshfield Medical Center-EC Cancer Center, Eau Claire
Marshfield Medical Center-Rice Lake, Rice Lake
Regions Hospital, Saint Paul
United Hospital, Saint Paul
Abbott-Northwestern Hospital, Minneapolis
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park
Mercy Hospital, Coon Rapids
Fairview Southdale Hospital, Edina
Mayo Clinic in Rochester, Rochester
NorthShore University HealthSystem-Glenbrook Hospital, Glenview
NorthShore University HealthSystem-Highland Park Hospital, Highland Park
Northwestern Medicine Lake Forest Hospital, Lake Forest
Northwestern Medicine Cancer Center Kishwaukee, DeKalb
Northwestern Medicine Cancer Center Delnor, Geneva
NorthShore University HealthSystem-Evanston Hospital, Evanston
Northwestern Medicine Cancer Center Warrenville, Warrenville
Northwestern University, Chicago
University of Illinois, Chicago
Carle Cancer Center, Urbana
Carle at The Riverfront, Danville
Carle Physician Group-Mattoon/Charleston, Mattoon
Carle Physician Group-Effingham, Effingham
Washington University School of Medicine, St Louis
Siteman Cancer Center-South County, St Louis
Siteman Cancer Center at West County Hospital, Creve Coeur
Mercy Hospital Saint Louis, St Louis
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha
Nebraska Methodist Hospital, Omaha
Oncology Associates PC, Omaha
University Medical Center New Orleans, New Orleans
Our Lady of the Lake Medical Oncology, Baton Rouge
University of Oklahoma Health Sciences Center, Oklahoma City
UCHealth University of Colorado Hospital, Aurora
Poudre Valley Hospital, Fort Collins
Cancer Care and Hematology-Fort Collins, Fort Collins
Medical Center of the Rockies, Loveland
UCHealth Greeley Hospital, Greeley
UCHealth Memorial Hospital Central, Colorado Springs
Memorial Hospital North, Colorado Springs
Saint Luke's Cancer Institute - Twin Falls, Twin Falls
Saint Luke's Cancer Institute - Fruitland, Fruitland
Saint Luke's Cancer Institute - Meridian, Meridian
Saint Luke's Cancer Institute - Nampa, Nampa
Saint Luke's Cancer Institute - Boise, Boise
Mayo Clinic Hospital in Arizona, Phoenix
City of Hope Comprehensive Cancer Center, Duarte
City of Hope at Irvine Lennar, Irvine
Epic Care-Dublin, Dublin
Epic Care Cyberknife Center, Walnut Creek
Epic Care Partners in Cancer Care, Emeryville
Clackamas Radiation Oncology Center, Clackamas
Legacy Mount Hood Medical Center, Gresham
Providence Willamette Falls Medical Center, Oregon City
Legacy Meridian Park Hospital, Tualatin
Providence Newberg Medical Center, Newberg
Legacy Good Samaritan Hospital and Medical Center, Portland
Providence Portland Medical Center, Portland
Providence Saint Vincent Medical Center, Portland
Oregon Health and Science University, Portland
Fred Hutchinson Cancer Center, Seattle
University of Washington Medical Center - Montlake, Seattle
Legacy Cancer Institute Medical Oncology and Day Treatment, Vancouver
Legacy Salmon Creek Hospital, Vancouver
Alaska Women's Cancer Care, Anchorage
Contra Costa Regional Medical Center, Martinez
Smilow Cancer Hospital-Derby Care Center, Derby
Smilow Cancer Hospital Care Center-Fairfield, Fairfield
Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury
Smilow Cancer Hospital Care Center at Greenwich, Greenwich
Smilow Cancer Hospital Care Center - Guilford, Guilford
Smilow Cancer Hospital Care Center at Saint Francis, Hartford
Yale University, New Haven
Yale-New Haven Hospital North Haven Medical Center, North Haven
Smilow Cancer Hospital Care Center at Long Ridge, Stamford
Smilow Cancer Hospital-Torrington Care Center, Torrington
Smilow Cancer Hospital Care Center-Trumbull, Trumbull
Smilow Cancer Hospital-Waterbury Care Center, Waterbury
Smilow Cancer Hospital Care Center - Waterford, Waterford
Mayo Clinic in Florida, Jacksonville
MaineHealth Maine Medical Center- Scarborough, Scarborough
Dana-Farber Cancer Institute, Boston
Memorial Sloan Kettering Basking Ridge, Basking Ridge
Memorial Sloan Kettering Monmouth, Middletown
Memorial Sloan Kettering Bergen, Montvale
Women and Infants Hospital, Providence
Smilow Cancer Hospital Care Center - Westerly, Westerly
Centro Comprensivo de Cancer de UPR, San Juan
National Cancer Institute (NCI)
NIH