Global Warming Impact of Nitrous Oxide

PHASE4CompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

June 29, 2022

Primary Completion Date

April 22, 2023

Study Completion Date

April 22, 2023

Conditions
Global Warming Effect of Nitrous Oxide
Interventions
DRUG

Nitrous oxide

In conventional nitrous oxide carrier group 2% Sevoflurane in O2-N2O (60 % FiO2) @3L/min will be delivered to achieve MAC 0.5.

DRUG

Nitrous oxide

In streamed-in nitrous oxide carrier group 2% Sevoflurane in O2 -Air (60 % FiO2) will be delivered @3.0L/min to achieve a MAC of 0.5. Then, the FGF will be decreased to 1.0 L (low flow) and N2O will be 'streamed-in' @ 40 %.

DRUG

Sevoflurane

Ventilation will be initiated with 2% sevoflurane in all the groups

Trial Locations (1)

110060

Sir Ganga Ram Hospital, New Delhi

All Listed Sponsors
lead

Sir Ganga Ram Hospital

OTHER