Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 5, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

July 30, 2026

Conditions
Chronic Rhinosinusitis (Diagnosis)
Interventions
DRUG

Lactobacillus sakei proBio65

Lanto Sinus probiotic Lactobacillus sakei is a currently available over the counter supplement from the common source kimchi and produced in South Korea. Patients will be instructed to mix 1 packet with lukewarm distilled or boiled water in 240mL NeilMed® sinus rinse bottle.

OTHER

Isotonic Saline Solution

Saline sinus irrigations (SAL group): NeilMed® Isotonic Sinus Rinse™ is marketed as a saline sinus irrigation formula. Subjects will be given instructions to mix one unlabeled packet (containing NeilMed® premixed buffered salt powder) with lukewarm distilled or boiled water in 240mL NeilMed® sinus rinse bottle.

Trial Locations (1)

60612

RECRUITING

University of Illinois Hospitals & Health Sciences System, Chicago

All Listed Sponsors
collaborator

Cures Within Reach

OTHER

lead

University of Illinois at Chicago

OTHER