NCT05421208View on ClinicalTrials.gov

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

December 1, 2025

Study Completion Date

December 1, 2026

Conditions
Post-acute COVID-19 SyndromePostural Tachycardia Syndrome (POTS)Long COVIDSARS CoV 2 Infection
Interventions
DIAGNOSTIC_TEST

Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls

Inflammatory and immune profile of post-COVID-19 POTS patients. Reduced PNS activity (vagal tone) in relation to persistent inflammation.

DIAGNOSTIC_TEST

Levels of inflammatory cytokine ( IL-6) in controls

Inflammatory and immune profile of healthy controls. Controls are the subjects who recovered from COVID-19 infection with no sequelae.

DIAGNOSTIC_TEST

Effect on inflammation after chronic PNS stimulation

Inflammatory biomarkers after restoring PNS function in post-COVID-19 POTS patients, by chronic transcutaneous vagus nerve stimulation (tVNS) in post COVID-19 POTS patients

Trial Locations (1)

37232

RECRUITING

Vanderbilt University Medical Center, Nashville

All Listed Sponsors
collaborator

American Heart Association

OTHER

lead

Vanderbilt University Medical Center

OTHER