Two-field Versus Three-field Lymph Node Dissection in ESCC After Neoadjuvant Therapy

NANot yet recruitingINTERVENTIONAL
Enrollment

323

Participants

Timeline

Start Date

July 1, 2022

Primary Completion Date

June 1, 2024

Study Completion Date

June 1, 2027

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
PROCEDURE

Two-Field lymph node dissection

"The right recurrent laryngeal nerve lymph node (106recR) will be dissected and subjected to the intra-operative frozen section pathology. If the 106recR lymph node has no metastasis, patients will be randomized to two groups at 1:1 ratio and receive esophagectomy with Two-Field or Three-Field lymph node dissection."

PROCEDURE

Three-Field lymph node dissection

"The right recurrent laryngeal nerve lymph node (106recR) will be dissected and subjected to the intra-operative frozen section pathology. If the 106recR lymph node has no metastasis, patients will be randomized to two groups at 1:1 ratio and receive esophagectomy with Two-Field or Three-Field lymph node dissection."

PROCEDURE

Three-Field lymph node dissection

"The right recurrent laryngeal nerve lymph node (106recR) will be dissected and subjected to the intra-operative frozen section pathology. If the 106recR lymph node has metastasis, esophagectomy and Three-Field lymph node dissection will be performed."

Trial Locations (1)

200032

Shanghai Zhongshan Hospital, Shanghai

All Listed Sponsors
collaborator

Baoji Central Hospital

OTHER

collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

collaborator

Suining Central Hospital

OTHER

collaborator

Jieyang People's Hospital

OTHER

collaborator

Second Affiliated Hospital of Nantong University

OTHER

collaborator

Taixing People's Hospital

OTHER

collaborator

Hebei Medical University Fourth Hospital

OTHER

collaborator

Suzhou Municipal Hospital

OTHER

collaborator

Fujian Provincial Hospital

OTHER

collaborator

Jining First People's Hospital

OTHER

collaborator

The General Hospital of Western Theater Command

OTHER

collaborator

Zhejiang Cancer Hospital

OTHER

collaborator

Shanghai Chest Hospital

OTHER

lead

Shanghai Zhongshan Hospital

OTHER

NCT05420480 - Two-field Versus Three-field Lymph Node Dissection in ESCC After Neoadjuvant Therapy | Biotech Hunter | Biotech Hunter