388
Participants
Start Date
November 23, 2023
Primary Completion Date
January 1, 2026
Study Completion Date
September 1, 2026
Transcutaneous Vagus Nerve Stimulation Paired with Tailor-Made Notched Music Therapy
The pulse frequency of vagus nerve stimulation is 25 Hz, the pulse width is 200 US, and the intensity is 1-10 mA. Tailor-made notched music is produced by filtering a frequency band of 1/2 octave width centered at the individual tinnitus frequency. When two sides of tinnitus frequencies are different, each side of music are filtered respectively, according to the different tinnitus frequency. When only have unilateral tinnitus or bilateral tinnitus in the same central frequency, both sides of music are filtered with the same tinnitus frequency. The tVNS and TMNM begin at the same time during treatment.
Tailor-made Notched Music Training
Tailor-made notched music is produced by filtering a frequency band of 1/2 octave width centered at the individual tinnitus frequency. When two sides of tinnitus frequencies are different, each side of music are filtered respectively, according to the different tinnitus frequency. When only have unilateral tinnitus or bilateral tinnitus in the same central frequency, both sides of music are filtered with the same tinnitus frequency. At the beginning of TMNMT, 10 seconds sham vagus nerve stimulation is output, whose parameters are as same as experimental group.
The First Affiliated Hospital with Nanjing Medical University
OTHER
Zhongshan People's Hospital, Guangdong, China
OTHER
Affiliated Zhuhai Hospital of Southern Medical University
UNKNOWN
Guangzhou Panyu Central Hospital
OTHER
Shenshan Medical Center, Memorial Hospital of Sun Yat-sen University
UNKNOWN
Eighth Affiliated Hospital, Sun Yat-sen University
OTHER
Second Affiliated Hospital of Guangzhou Medical University
OTHER
Southern Medical University, China
OTHER
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER