NCT05414292View on ClinicalTrials.gov

Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)

NARecruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

August 6, 2021

Primary Completion Date

May 1, 2027

Study Completion Date

May 1, 2027

Conditions
Muscle AtrophyAge-Related Sarcopenia
Interventions
DRUG

Rapamune (sirolimus) 1Mg Tablet

Take Rapamune to see the effect on muscle structure and function during a 14 week unilateral resistance exercise training programme.

BEHAVIORAL

Unilateral resistance exercise training

Participants will complete unilateral leg extension resistance training 3 times per week for 14 weeks at 75% of their 1 repetition maximum

Trial Locations (1)

DE22 3DT

RECRUITING

University of Nottingham School of Medicine, Derby

All Listed Sponsors
collaborator

University of Oxford

OTHER

lead

University of Nottingham

OTHER