Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV

NAActive, not recruitingINTERVENTIONAL

Enrollment

180

Participants

Timeline

Start Date

March 22, 2023

Primary Completion Date

August 24, 2025

Study Completion Date

August 24, 2025

Conditions

Cervical CancerCIN2CIN3Human Immunodeficiency VirusHuman Papillomavirus

Interventions

DRUG

5 Fluorouracil (5 FU) Cream

Intravaginal topical chemotherapy, 5-fluorouracil cream

DRUG

Placebo

Intravaginal topical placebo cream

Trial Locations (1)

Clinical HIV Research Unit Temba Lethu Wing Helen Joseph Hospital, Westdene

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

UNC Lineberger Comprehensive Cancer Center

OTHER