Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 1, 2021

Primary Completion Date

October 1, 2022

Study Completion Date

November 1, 2022

Conditions
Oral MucositisORASOral InfectionOral Ulcer
Interventions
COMBINATION_PRODUCT

Combination of diclofenac potassium and propolis

Patients will be divided into two groups: the first one will be treated with a combination of diclofenac 3% (10 mg/g, 60 g, EMS) and Propolis 5% gel and the second one is placebo group. Participants will be allocated randomly. The patients will be asked to apply gel 2 times per day. The patients will be instructed, not to eat or drink for 1 h after application of the gel

OTHER

placebo

placebo

Trial Locations (1)

11825

Al Azhar university, Cairo

All Listed Sponsors
lead

Al-Azhar University

OTHER