Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome

Enrolling by invitationOBSERVATIONAL
Enrollment

52

Participants

Timeline

Start Date

July 10, 2022

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
ObeseHealthyBariatric Surgery Candidate
Interventions
PROCEDURE

Endoscopic biopsy

Upper small intestinal biopsies from patients undergoing BS will be collected during routine standard of care screening EGD and again from the same patients at 1 year during routine standard of care surveillance EGD (esophageal reflux screening/surveillance). Biopsy-derived enteroid cultures and tissue samples from pre- and one-year post BS will be examined for expression level of sugar transporters and gluconeogenic enzymes; glucose and fructose absorption

Trial Locations (1)

32224

Mayo Clinic Florida, Jacksonville

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER