Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain

NARecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

July 7, 2022

Primary Completion Date

March 1, 2025

Study Completion Date

September 1, 2026

Conditions
Knee OsteoarthritisPersistent Postsurgical PainChronic Knee Pain
Interventions
PROCEDURE

Conventional Radiofrequency ablation of the genicular nerves

Conventional Radiofrequency treatment of the genicular nerves of the knee blocks the transmission of painful stimuli from the sensory genicular nerves of the knee to the central nervous system by means of a thermal lesion created using RF current.

PROCEDURE

Cooled Radiofrequency ablation of the genicular nerves

Cooled RF treatment causes a larger lesion size compared to conventional RF by means of internal cooling of the probe.

PROCEDURE

Sham procedure

Sham procedure with placing of needles subcutaneously.

Trial Locations (15)

1070

RECRUITING

ULB Erasme, Brussels

1200

ACTIVE_NOT_RECRUITING

UCL Saint-Luc, Brussels

2300

RECRUITING

AZ Turnhout, Turnhout

2650

RECRUITING

UZ Antwerpen, Antwerp

2930

ACTIVE_NOT_RECRUITING

AZ Klina, Brasschaat

3000

RECRUITING

UZ Leuven, Leuven

3500

RECRUITING

Jessa Ziekenhuis, Hasselt

3600

RECRUITING

Ziekenhuis Oost-Limburg AV, Genk

4000

RECRUITING

CHR de la Citadelle, Liège

ACTIVE_NOT_RECRUITING

CHU Liège, Liège

8500

ACTIVE_NOT_RECRUITING

AZ Groeninge, Kortrijk

8800

RECRUITING

AZ Delta, Roeselare

Unknown

RECRUITING

AZ Maria Middelares, Ghent

6815 AD

ACTIVE_NOT_RECRUITING

Rijnstate, Arnhem

6229 HX

RECRUITING

MUMC, Maastricht

All Listed Sponsors
collaborator

Belgium Health Care Knowledge Centre

OTHER_GOV

collaborator

Klinische Epidemiologie en Medical Technology Assessment

UNKNOWN

lead

Ziekenhuis Oost-Limburg

OTHER