StEroids in hospitaLized patiEnts With Covid-19 in The Netherlands.

CompletedOBSERVATIONAL
Enrollment

2,465

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

December 1, 2023

Study Completion Date

December 1, 2023

Conditions
COVID-19
Interventions
DRUG

Steroids

"Description of the intervention in each of the work packages:~* WP1A admission: Steroid dose \>6mg/day dexamethasone equivalent will be compared to control (steroid = 6mg/day dexamethasone or equivalent steroid).~* WP1B late: After 10 days of dexamethasone therapy patients are stratified in high-dose steroids (\> 6 mg dexamethasone or equivalent steroid) or no steroids up to day 28.~* WP2 ICU admission: High-dose steroids (dexamethasone \>6 mg daily or equivalent corticosteroids) compared to dexamethasone 6 mg up to 72 hours after admission~* WP3 ICU late: After dexamethasone 6 mg for 10 days patients are stratified in high-dose steroids (dexamethasone \>6 mg daily or equivalent corticosteroids) or no steroids up to day 28."

Trial Locations (1)

Unknown

Erasmus MC, Rotterdam

All Listed Sponsors
collaborator

Amsterdam UMC

OTHER

collaborator

OLVG

NETWORK

collaborator

Isala

OTHER

collaborator

St. Antonius Hospital

OTHER

collaborator

Academisch Ziekenhuis Groningen

OTHER

collaborator

Amphia Hospital

OTHER

collaborator

Maasstad Hospital

OTHER

lead

Henrik Endeman

OTHER