The Role of Migraine Prophylaxis Agent Topiramate in Treating Patients With Sudden Sensorineural Hearing Loss

PHASE2RecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

October 17, 2022

Primary Completion Date

May 31, 2025

Study Completion Date

September 30, 2025

Conditions
Sudden DeafnessSudden Sensorineural Hearing Loss
Interventions
DRUG

Topiramate

The topiramate arm receives additional oral topiramate for 6 weeks. The dose of topiramate is started from 25mg orally daily with the weekly escalation of 25mg to a maximum of 100mg.

DRUG

Systemic Steroids

Both groups receive a systemic steroid with/without intratympanic steroids as the standard treatment of SSNHL.

Trial Locations (1)

236

RECRUITING

New Taipei Municipal Tucheng Hospital, New Taipei City

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER