The RAFT ECT Study

NARecruitingINTERVENTIONAL
Enrollment

154

Participants

Timeline

Start Date

March 22, 2023

Primary Completion Date

August 31, 2025

Study Completion Date

January 31, 2026

Conditions
Major Depressive Episode
Interventions
PROCEDURE

Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy

UBRUL-FP involves ultrabrief right unilateral ECT delivered using a novel frontoparietal montage, where the anterior electrode is shifted frontally to a position above the midpoint of the right eye to avoid temporal lobe stimulation (and reduce memory side effects). UBRUL-FP will be delivered using standard ECT devices.

PROCEDURE

Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy

UBRUL-TP is the standard form of ultrabrief right unilateral ECT, using the conventional temporoparietal (d'Elia) electrode placement, where the anterior electrode is placed over the right temporal lobe. UBRUL-TP will be delivered using standard ECT devices.

Trial Locations (7)

2065

RECRUITING

Ramsay Clinic Northside, Sydney

2282

RECRUITING

Ramsay Clinic Lakeside, Warners Bay

3004

RECRUITING

Ramsay Clinic Albert Road, Melbourne

4215

RECRUITING

Gold Coast University Hospital (GCUH), Gold Coast

29425

RECRUITING

Medical University of South Carolina, Charleston

30322

RECRUITING

Emory University, Atlanta

30912

RECRUITING

Medical College of Georgia, Augusta University, Augusta

All Listed Sponsors
collaborator

National Health and Medical Research Council, Australia

OTHER

collaborator

Ramsay Clinic Albert Road, Australia

UNKNOWN

collaborator

Ramsay Clinic Lakeside, Australia

UNKNOWN

collaborator

Ramsay Clinic Northside, Australia

UNKNOWN

collaborator

Gold Coast Hospital and Health Service

OTHER_GOV

collaborator

Augusta University

OTHER

collaborator

Medical University of South Carolina

OTHER

collaborator

The University of New South Wales

OTHER

collaborator

Emory University

OTHER

lead

The George Institute

OTHER

NCT05402657 - The RAFT ECT Study | Biotech Hunter | Biotech Hunter