Functional and Ultrasound Guided Resection of Glioblastoma

NARecruitingINTERVENTIONAL
Enrollment

357

Participants

Timeline

Start Date

November 1, 2020

Primary Completion Date

October 31, 2025

Study Completion Date

November 30, 2025

Conditions
Glioma Glioblastoma Multiforme
Interventions
OTHER

Standard of Care

Neuronavigation and intraoperative 5-ALA

OTHER

Additional pre- and intra-operative imaging

Additional DTI scan during routine pre-operative tumour MRI scan, additional use of intraoperative ultrasound in addition to normal to standard of care (Neuronavigation and intraoperative 5-ALA)

Trial Locations (24)

B15 2TH

NOT_YET_RECRUITING

Queen Elizabeth Hospital, University Hospitals Birmingham NHSFT, Birmingham

BN2 5BE

NOT_YET_RECRUITING

Royal Sussex County Hospital, Brighton

BS10 5NB

RECRUITING

Southmead Hospital, North Bristol NHST, Bristol

CB2 0QQ

RECRUITING

Addenbrookes Hospital, Cambridge University NHSFT, Cambridge

CF14 4XW

RECRUITING

University Hospital of Wales, Cardiff & Vale University Health Board, Cardiff

CV2 2DX

NOT_YET_RECRUITING

University Hospital, Coventry, Coventry

DD2 1SG

RECRUITING

Ninewells Hospital, NHS Tayside, Dundee

EH16

RECRUITING

The Royal Infirmary of Edinburgh, NHS Lothian, Edinburgh

HU3 2JZ

RECRUITING

Hull Royal Infirmary, Hull

LS1 3EX

RECRUITING

Leeds General Infirmary, Leeds

L9 7LJ

RECRUITING

The Walton Centre, Liverpool

E1 1BB

RECRUITING

Royal London Hospital, Barts Health NHS Trust, London

SE5 9RS

RECRUITING

King's College Hospital, London

W6 8RF

RECRUITING

Charing Cross Hospital/St Mary's, Imperial College Healthcare NHS Trust, London

TS4 3BW

RECRUITING

James Cook University Hospital, South Tees Hospitals NHSFT, Middlesbrough

NE1 4LP

NOT_YET_RECRUITING

Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHSFT, Newcastle upon Tyne

NG7 2UH

RECRUITING

Queen's Medical Centre, Nottingham University Hospitals NHST, Nottingham

OX3 9DU

RECRUITING

The John Radcliffe Hospital, Oxford University Hospitals NHSFT, Oxford

PL6 8DH

RECRUITING

Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth

PR2 9HT

NOT_YET_RECRUITING

Royal Preston Hospital, Lancashire Teaching Hospitals NHSFT, Preston

RM7 0AG

NOT_YET_RECRUITING

Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHST, Romford

S10 2JF

NOT_YET_RECRUITING

Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield

Unknown

RECRUITING

Southampton General Hospital, University Hospital Southampton NHSFT, Southampton

ST4 6QG

RECRUITING

Royal Stoke University Hospital, University Hospitals of North Midlands NHST, Stoke-on-Trent

All Listed Sponsors
collaborator

Imperial College Healthcare NHS Trust

OTHER

collaborator

Efficacy and Mechanism Evaluation (EME) Programme

OTHER

lead

University of Oxford

OTHER