The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery

NAEnrolling by invitationINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 10, 2022

Primary Completion Date

June 1, 2024

Study Completion Date

October 1, 2024

Conditions
AnesthesiaSurgery
Interventions
PROCEDURE

Conventional positive end-expiratory pressure(PEEP)

Positive end-expiratory pressure is the mechanical ventilator that generates positive pressure during the inspiratory phase to pass gas into the lungs. When the airway opens at the end of expiration, the airway pressure remains above atmospheric pressure to prevent the alveoli from shrinking and collapsing.In this intervention arm It will be set to 5 cmH2O until the end of the operation.

PROCEDURE

Lung dynamic compliance guided positive end-expiratory pressure(PEEP)

Positive end-expiratory pressure is the mechanical ventilator that generates positive pressure during the inspiratory phase to pass gas into the lungs. When the airway opens at the end of expiration, the airway pressure remains above atmospheric pressure to prevent the alveoli from shrinking and collapsing.In this intervention arm It will be set to individual value until the end of the operation.The individualized values are obtained by observing the maximum Lung dynamic compliance during PEEP titration.

Trial Locations (1)

518038

Shenzhen Children's Hospital, Shenzhen

All Listed Sponsors
lead

Jiaxiang Chen

OTHER