60
Participants
Start Date
June 10, 2022
Primary Completion Date
June 1, 2024
Study Completion Date
October 1, 2024
Conventional positive end-expiratory pressure(PEEP)
Positive end-expiratory pressure is the mechanical ventilator that generates positive pressure during the inspiratory phase to pass gas into the lungs. When the airway opens at the end of expiration, the airway pressure remains above atmospheric pressure to prevent the alveoli from shrinking and collapsing.In this intervention arm It will be set to 5 cmH2O until the end of the operation.
Lung dynamic compliance guided positive end-expiratory pressure(PEEP)
Positive end-expiratory pressure is the mechanical ventilator that generates positive pressure during the inspiratory phase to pass gas into the lungs. When the airway opens at the end of expiration, the airway pressure remains above atmospheric pressure to prevent the alveoli from shrinking and collapsing.In this intervention arm It will be set to individual value until the end of the operation.The individualized values are obtained by observing the maximum Lung dynamic compliance during PEEP titration.
Shenzhen Children's Hospital, Shenzhen
Jiaxiang Chen
OTHER