Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906)

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

September 14, 2022

Primary Completion Date

May 31, 2028

Study Completion Date

October 31, 2028

Conditions
Wilms Tumor
Interventions
DRUG

Vincristine

IV, D1-D22-D43 and D64

DRUG

Irinotecan

Oral, 5 days/week during W1,W2,W7 and W8 (D1 to D5, D8 to D12, D43 to D47, D50 to D54)

DRUG

Temozolomide

Oral,3 weeks in a row, twice per cycle (D1 to D21, D43 to D63)

DRUG

Etoposide

Oral, 3 weeks in a row, twice per cycle (D22 to D42, D64 to D84)

DRUG

Cis-Retinoic acid

Oral, 2 weeks in a row, thrice per cycle (D15 to D28, D43 to D56, D71 to D84)

Trial Locations (18)

13005

RECRUITING

"Hôpital pour Enfants La Timone AP-HM", Marseille

33076

RECRUITING

CHRU de Bordeaux Hôpital des Enfants, Bordeaux

34295

NOT_YET_RECRUITING

CHU de MONTPELLIER - Hôpital Arnaud de Villeneuve, Montpellier

35203

RECRUITING

CHU Hôpital Sud, Rennes

38043

RECRUITING

CHU GRENOBLE ALPES - Hôpital COUPLE ENFANT, Grenoble

44093

RECRUITING

CHU Nantes, Nantes

54500

RECRUITING

CHRU NANCY - Hôpital d'Enfants, Vandœuvre-lès-Nancy

59020

RECRUITING

Centre Oscar Lambret, Lille

67098

RECRUITING

CHRU Strasbourg - Hôpital de Hautepierre, Strasbourg

69373

RECRUITING

Centre Léon Bérard, Lyon

70034

RECRUITING

CHU Toulouse - Hôpital des Enfants, Toulouse

75012

RECRUITING

Hôpital Armand-TROUSSEAU, Paris

76000

RECRUITING

Chu Rouen, Rouen

80054

NOT_YET_RECRUITING

CHU Amiens Picardie, Amiens

94805

RECRUITING

Gustave ROUSSY, Villejuif

Unknown

RECRUITING

CHU de Besancon, Besançon

NOT_YET_RECRUITING

CHU La Réunion, Saint-Denis

06202

RECRUITING

CHU de Nice - Hôpital Archet 2, Nice

All Listed Sponsors
lead

Centre Oscar Lambret

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