A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer

AK112 via intravenous (IV) infusion until disease progression or unacceptable toxicity

AK117 via intravenous (IV) infusion until disease progression or unacceptable toxicity

Oxaliplatin via IV infusion

Capecitabine via oral,The total daily dose was 2000mg/sqm, Each cycle was administered for 2 consecutive weeks, followed by a week of rest, with a treatment cycle every 21 days

Irinotecan via IV infusion

Leucovorin via IV infusion

5-fluorouracil via IV infusion