Cutaneous Silent Period Assessment in Primary Sjögren's Syndrome

CompletedOBSERVATIONAL
Enrollment

72

Participants

Timeline

Start Date

January 4, 2021

Primary Completion Date

January 28, 2022

Study Completion Date

February 28, 2022

Conditions
Small Fiber NeuropathyPrimary Sjögren Syndrome
Interventions
DIAGNOSTIC_TEST

cutaneous silent period (CSP) measurement

CSP recordings are performed in the upper extremities using the same surface bar recording electrodes. Filters are set at 2 Hertz (Hz) to 10 kilo Hz, sensitivity is 200 microVolts (µV) and sweep speed is set at 200 milliseconds (ms). Stimulating electrode is placed on the index finger and recording bar electrode is placed on the abductor pollicis brevis (APB) muscle. During steady submaximal (50% of the maximal contraction) thumb abduction, 10 consecutive painful electrical stimuli of standard 80-milli Ampere (mA) intensity and 0.5-ms duration are applied to the index finger and responses are superimposed. CSP latency and duration are calculated and recorded. CSP latency is defined as the time between the stimulation and the onset of the silent period. CSP duration is calculated as the time interval between the beginning and end of the CSP.

Trial Locations (1)

34899

Marmara University Pendik Education and Research Hospital, Istanbul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Marmara University

OTHER

NCT05380804 - Cutaneous Silent Period Assessment in Primary Sjögren's Syndrome | Biotech Hunter | Biotech Hunter