Application of Linaclotide Capsule in Bowel Preparation for Patients at High Risk of Inadequate Bowel Preparation

NACompletedINTERVENTIONAL
Enrollment

720

Participants

Timeline

Start Date

August 1, 2022

Primary Completion Date

June 30, 2023

Study Completion Date

July 15, 2023

Conditions
Colonoscopy
Interventions
DRUG

3 L PEG + linaclotide

Participants take a linaclotide capsule on the day before colonoscopy at least 30 minutes before the first meal (if this is impossible, take the capsule as early as possible on that day). Participants take 1 L polyethylene glycol electrolyte solution within 1 hour from 8 p.m the night before the examination and take another linaclotide capsule and 2 L polyethylene glycol electrolyte solution 4 hours before the colonoscopy.

DRUG

3 L PEG + placebo

Participants take a placebo capsule on the day before colonoscopy at least 30 minutes before the first meal (if this is impossible, take the capsule as early as possible on that day). Participants take 1 L polyethylene glycol electrolyte solution within 1 hour from 8 p.m the night before the examination and take another placebo capsule and 2 L polyethylene glycol electrolyte solution 4 hours before the colonoscopy.

Trial Locations (8)

710004

Xi'an Central Hospital, Xi'an

Xi'an Jiaotong University Second Affiliated Hospital, Xi'an

710036

Air Force 986 Hospital, Xi'an

Xijing Hospital of Digestive Diseases, Xi'an

710068

Shaanxi Provincial People's Hospital, Xi'an

750002

Ningxia Hui Autonomous Region People's Hospital, Yinchuan

041000

Linfen Central Hospital, Linfen

Unknown

The Second Hospital of Shanxi Medical University, Taiyuan

All Listed Sponsors
lead

Zhiguo Liu

OTHER