Sucrose at Triage for Acute Gastroenteritis Episode in Children

NACompletedINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

May 11, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Gastroenteritis AcuteVomiting
Interventions
DIETARY_SUPPLEMENT

sucrose

The experimental arm will receive 1.5 ml/kg of the sucrose solution at triage (once). The composition of the homemade sucrose solution used in our emergency department is 3.5 g of table sugar (sucrose) mixed with 10 ml of water. For this double-blind study, we replaced water with diluted juice (see standard arm description) to obtain a solution with the same appearance as the standard arm. With the idea of correcting ketosis, we chose to provide the same amount of sugar as we do in hypoglycemia (0.4-0.5 g/kg of dextrose) to participants in the intervention group, which represents 1.5 ml/kg of the sucrose solution containing 0.4 g of sucrose/mL for a total of 0.6 g/kg of sucrose.

DIETARY_SUPPLEMENT

Standard rehydration solution

This group will receive 1.5 mL/kg of diluted juice composed of juice (apple or orange) and water in equal proportion once at triage. This solution contains 0.05 g/ml of sucrose for a total of 0.075 g/kg of sucrose (eight times less than the intervention arm).

Trial Locations (1)

H3T1C5

Sainte-Justine Hospital, Montreal

All Listed Sponsors
lead

Jocelyn Gravel

OTHER