Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

NARecruitingINTERVENTIONAL
Enrollment

900

Participants

Timeline

Start Date

August 5, 2022

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2028

Conditions
Cardiac Arrest, Out-Of-HospitalHypothermia, InducedHypoxia-Ischemia, Brain
Interventions
DEVICE

Therapeutic Hypothermia

"Participants will receive therapeutic hypothermia for the assigned number of hours with controlled rewarming,~A zero hour cooling duration (normothermia) treatment arm will be opened for enrollment if there is not an increase in the treatment effect across the durations. Alternatively, longer durations (84 or 96 hours) will be opened for enrollment if the treatment effects are increasing (rather than plateauing or decreasing) through 72 hours."

Trial Locations (54)

1142

RECRUITING

Starship Children's Hospital, Grafton

3052

RECRUITING

Royal Children's Hospital, Parkville

3168

RECRUITING

Monash Medical Centre, Clayton

4101

RECRUITING

Queensland Children's Hospital, Brisbane

5006

RECRUITING

Women's and Children's Hospital, North Adelaide

10029

RECRUITING

Mount Sinai Icahn / Kravis Children's Hospital, New York

11040

RECRUITING

Cohen Children's Medical Center of NY / Northwell Health, New Hyde Park

14203

RECRUITING

University of Buffalo / Oishei Children's Hospital, Buffalo

15224

RECRUITING

Children's Hospital of Pittsburgh (UPMC), Pittsburgh

17033

RECRUITING

Penn State University / Penn State Children's Hospital, Hershey

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

21201

RECRUITING

University of Maryland Children's Hospital, Baltimore

21287

RECRUITING

Johns Hopkins Medicine Children's Center, Baltimore

33124

RECRUITING

University of Miami, Miami

35233

RECRUITING

University of Alabama at Birmingham / Children's of Alabama, Birmingham

38104

RECRUITING

University of Tennesses Health Center / Le Bonheur Children's, Memphis

43205

RECRUITING

Ohio State University / Nationwide Children's Hospital, Columbus

44308

RECRUITING

Children's Hospital Medical Center of Akron, Akron

45229

RECRUITING

Cincinnati Children's Hospital, Cincinnati

45404

RECRUITING

Dayton Children's Hospital, Dayton

46202

RECRUITING

Riley Children's Health, Indianapolis

48109

RECRUITING

University of Michigan CS Mott Children's Hospital, Ann Arbor

48201

RECRUITING

Children's Hospital of Michigan, Detroit

52242

RECRUITING

University of Iowa, Carver College of Medicine, Iowa City

53226

RECRUITING

Children's Wisconsin, Milwaukee

53705

RECRUITING

American Family Children's Hospital, Madison

55454

WITHDRAWN

University of Minnesota Fairview Masonic Children's Hospital, Minneapolis

60611

RECRUITING

Ann & Robert Lurie Children's Hospital of Chicago, Chicago

60637

RECRUITING

Comer Children's Hospital, University of Chicago, Chicago

61637

RECRUITING

Children's Hospital of Illinois, Peoria

63110

RECRUITING

Washington University / St. Louis Children's Hospital, St Louis

75235

RECRUITING

Children's Medical Center of Dallas, Dallas

77030

RECRUITING

Texas Children's Hospital, Baylor, Houston

78229

RECRUITING

The University of Texas Health Science Center at San Antonio, San Antonio

84108

WITHDRAWN

Primary Children's Hospital, University of Utah School of Medicine, Salt Lake City

85016

RECRUITING

Phoenix Children's Hospital, Phoenix

85719

RECRUITING

Banner University Medical Center - Tucson, Tucson

90027

RECRUITING

Children's Hospital of Los Angeles, Los Angeles

90095

RECRUITING

University of California Los Angeles (UCLA) Mattel Children's Hospital, Los Angeles

94158

RECRUITING

University of California - San Francisco (UCSF) Benioff Children's Hospital San Francisco, San Francisco

94609

RECRUITING

University of California - Oakland / UCSF Benoiff Children's Hospital Oakland, Oakland

95050

RECRUITING

Stanford, Santa Clara

95817

RECRUITING

University of California, Davis, Sacramento

97239

RECRUITING

Oregon Health & Science University Doernbecher Children's Hospital, Portland

90806-1701

RECRUITING

Memorial Health - Miller Children's and Women's Hospital of Long Beach, Long Beach

92868-4203

RECRUITING

Children's Hospital of Orange County, Orange

32610-0296

RECRUITING

University of Florida (UF) Health Shands Children's Hospital, Gainesville

02114

RECRUITING

MassGeneral Hospital for Children, Boston

14642-8667

RECRUITING

University of Rochester Medical Center, Rochester

27599-7220

RECRUITING

The University of North Carolina at Chapel Hill, Chapel Hill

Unknown

RECRUITING

Gold Coast University Hospital, Southport

RECRUITING

Perth Children's Hospital, Nedlands

RECRUITING

The Hospital for Sick Children, Toronto

RECRUITING

Birmingham Children's Hospital, United Kingdom, Birmingham

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Kennedy Krieger Institute, Baltimore, MD

UNKNOWN

lead

University of Michigan

OTHER