A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa

NARecruitingINTERVENTIONAL
Enrollment

648

Participants

Timeline

Start Date

February 7, 2024

Primary Completion Date

May 1, 2027

Study Completion Date

May 1, 2027

Conditions
HIV InfectionsAIDSVirologic Failure
Interventions
OTHER

Standard of Care treatment strategy

Management of virologic failure on TLD using the Standard of Care strategy

OTHER

Individualized Care treatment strategy

Management of virologic failure on TLD using the Individualized Care strategy

OTHER

Immediate Switch

Management of virologic failure on TLD using the Immediate Switch strategy

Trial Locations (3)

Unknown

RECRUITING

RK Khan Hospital Clinic, Durban

RECRUITING

Mbarara City Clinic, Mbarara

RECRUITING

Mbarara Regional Referral Hospital Immune Suppression Syndrome Clinic, Mbarara

All Listed Sponsors
collaborator

Mbarara University of Science and Technology

OTHER

collaborator

University of KwaZulu

OTHER

collaborator

University of California, San Francisco

OTHER

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Massachusetts General Hospital

OTHER