300
Participants
Start Date
November 1, 2022
Primary Completion Date
October 31, 2027
Study Completion Date
October 31, 2028
Mitoquinone
Mito-Q is a supplement that targets mitochondrial function. Linking a triphenyl-phosphonium cation to coenzyme-Q, to produce Mito-Q, results in a lipophilic compound, which, due to the large mitochondrial membrane potential, selectively accumulates within mitochondria. This targeted antioxidant approach results in 50- to 100-fold more Mito-Q accumulation compared to non-targeted antioxidant delivery.
Placebo
A placebo will be used in combination with exercise rehabilitation allowing for a double blinded placebo controlled design.
RECRUITING
VA Salt Lake City Health Care System, Salt Lake City, UT, Salt Lake City
VA Office of Research and Development
FED