Fruquintinib DDI Study With P-gp and BCRP Substrates

PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

March 2, 2022

Primary Completion Date

April 22, 2022

Study Completion Date

April 22, 2022

Conditions
Metastatic Colorectal Cancer
Interventions
DRUG

Fruquintinib

Fruquintinib will be administered as a single oral 5mg dose on the morning of day 5

DRUG

Dabigatran Etexilate

Dabigatran Etexilate will be administered as a single oral dose 150mg on the morning of day 1 and morning of day 5

DRUG

Rosuvastatin

Rosuvastatin will be administered as a single oral dose 10mg on the morning of day 1 and the morning of day 5

Trial Locations (1)

78744

PPD Development, Austin

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Hutchmed

INDUSTRY

NCT05368805 - Fruquintinib DDI Study With P-gp and BCRP Substrates | Biotech Hunter | Biotech Hunter