Air Pollution and Development in the Boricua Youth Study

NAEnrolling by invitationINTERVENTIONAL
Enrollment

182

Participants

Timeline

Start Date

January 23, 2023

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Pollution; ExposureNeurodevelopmental Disorders
Interventions
OTHER

MRI task

Task fMRI (Simon) \[ Time Frame: Children will undergo MRI scans when they are 6-11 years of age. \] Children will also complete a task, which will allow exploratory analyses of the functionality of attention-related neural circuits. The Simon fMRI task is a non-verbal task equivalent to the Stroop that tests sustained attention and inhibitory control and discriminates children with and without ADHD. Exploratory fMRI time-series data for each participant will be modeled using a general linear model with 3 predictors: congruent correct, incongruent correct, and incorrect. Contrast images for each participant (e.g., incongruent-minus-congruent) will be generated and entered into a group-level random-effects model. Analyses are exploratory, and will focus on frontal lobe activity during each type of trial.

Trial Locations (1)

10032

New York State Psychiatric Institute, New York

All Listed Sponsors
collaborator

University of Puerto Rico

OTHER

collaborator

National Institute of Environmental Health Sciences (NIEHS)

NIH

lead

New York State Psychiatric Institute

OTHER