In-line Mechanical Insufflation-Exsufflation in the Management of Ventilated Patients

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

July 1, 2015

Primary Completion Date

July 1, 2018

Study Completion Date

July 1, 2018

Conditions
Ventilation Therapy; ComplicationsAirway Clearance Impairment
Interventions
DEVICE

Mechanical In-Line Inexsufflation

In-line mechanical inexsufflation (IL-MIE) is a new method for performing MIE in intubated patients, which overcomes the drawbacks of MIE for ICU use . IL-MIE devices are integrated in-line with the patient's ventilator circuit, and do not themselves perform insufflations. Rather, the regular inspiration provided by the ventilator serves as the insufflation phase of each simulated cough, and the IL-MIE device performs only exsufflation, timing the onset of each exsufflation to the beginning of passive exhalation. Figure 1 demonstrates the setup and mode of operation of an IL-MIE device. The concept of IL-MIE was first developed by one of the authors (EB) in the Department of Respiratory Rehabilitation of ALYN Hospital in Jerusalem, Israel.

PROCEDURE

catheter suction

catheter suction is the standard, routine method for clearing secretions from the airway of a ventilated subject, by means of inserting a catheter into the endotracheal tube.

All Listed Sponsors
collaborator

Beijing Anzhen Hospital

OTHER

lead

Alyn Pediatric & Adolescent Rehabilitation Hospital

OTHER

NCT05365620 - In-line Mechanical Insufflation-Exsufflation in the Management of Ventilated Patients | Biotech Hunter | Biotech Hunter