Alveolar and Serum sRAGE in Severe Asthma in Children

RecruitingOBSERVATIONAL
Enrollment

85

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

June 1, 2024

Study Completion Date

June 1, 2024

Conditions
Asthma in Children
Interventions
DIAGNOSTIC_TEST

bronchial endoscopy with bronchoalveolar lavage (LBA)

Bronchial endoscopy under laryngeal mask and general anesthesia. BAL of saline at room temperature of 3 milliliters per kilogram limited to 20 milliliters x 3 according to recommendations

DIAGNOSTIC_TEST

Blood sampling

collection of 5 milliliters of blood for total white cells count, C-Reactive Protein, specific immunoglobulin E assays, serum sRAGE assay

Trial Locations (1)

63000

RECRUITING

CHU de Clermont-Ferrand, Clermont-Ferrand

All Listed Sponsors
lead

University Hospital, Clermont-Ferrand

OTHER