NCT05362539View on ClinicalTrials.gov

Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria

NACompletedINTERVENTIONAL

Enrollment

246

Participants

Timeline

Start Date

February 1, 2019

Primary Completion Date

June 1, 2021

Study Completion Date

April 1, 2022

Conditions

Bladder Cancer

Interventions

PROCEDURE

Cystoscopy

diagnostic cystoscopy for detection of any bladder lesions

DIAGNOSTIC_TEST

Computed tomography

Computed tomography for patients to exclude bladder lesions

GENETIC

DNA hypermethylation assay

DNA hypermethylation assay of six genes (GATA4, P16, P14, APC, CDH1 and CD99)

DIAGNOSTIC_TEST

Urine cytology

voided urine cytology for all patients

Trial Locations (1)

35516

Mansoura Urology and Nephrology Center, Al Mansurah

All Listed Sponsors

lead

Mansoura University

OTHER

NCT05362539 - Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria | Biotech Hunter | Biotech Hunter