New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 14, 2022

Primary Completion Date

May 14, 2026

Study Completion Date

May 15, 2026

Conditions
First Trimester AbortionSurgical AbortionMiscarriage With Afibrinogenemia
Interventions
DEVICE

MateRegen® gel (BioRegen)

Modification of Hyaluronic acid structure to 3-dimensional self-cross-linked network structure enables all-dimensional coverage of tissue surface to enhance better healing process. Self-cross-linked HA hydrogels can maintain the biocompatibility and biodegradability that characterize the unmodified material. Moreover, high dynamic viscosity enables continuous indwelling in the uterine cavity. The gel could provide precise regulation, and degradation and absorption time prolonged to 7-14 days post operatively, which completely cover key postoperative healing period (5-7 days), at the highest time of intrauterine adhesion formation.

Trial Locations (1)

Unknown

RECRUITING

The Chinese University of Hong Kong, Hong Kong

All Listed Sponsors
collaborator

Health and Medical Research Fund

OTHER_GOV

lead

Chinese University of Hong Kong

OTHER