Low Dose Prasugrel vs Clopidogrel for Stenting or Flow Diverter for Unruptured Aneurysm

PHASE4UnknownINTERVENTIONAL
Enrollment

406

Participants

Timeline

Start Date

June 13, 2022

Primary Completion Date

July 31, 2025

Study Completion Date

August 31, 2025

Conditions
Intracranial Aneurysm
Interventions
DRUG

Prasugrel group

Prescribe the drugs according to the assigned group, and take them 5 days before the procedure. Perform platelet function test (VerifyNow assay; Accumetrics, San Diego, California) one day before the procedure to check the P2Y12 reaction reactivity. And the hyporesponsive group patient is given prasugrel 5mg once. And aspirin 100mg and prasugrel 5mg will be maintained for 30 days.

DRUG

Clopidogrel group

Prescribe the drugs according to the assigned group, and take them 5 days before the procedure. Perform platelet function test (VerifyNow assay; Accumetrics, San Diego, California) one day before the procedure to check the P2Y12 reaction reactivity. And the hyporesponsive group patient is given pletaal 100mg once. And aspirin 100mg and clopidogrel 75mg mg will be maintained for 30 days.

Trial Locations (1)

16995

RECRUITING

Yongin Severance hospital, Yonsei university college of medicine, Gyeonggi-do

Sponsors
All Listed Sponsors
collaborator

Severance Hospital

OTHER

collaborator

Gangnam Severance Hospital

OTHER

collaborator

Bucheon St. Mary's Hospital

OTHER

collaborator

International St. Mary's Hospital

UNKNOWN

collaborator

Ewha Woman's University Seoul Hospital

UNKNOWN

lead

Yonsei University

OTHER

NCT05359224 - Low Dose Prasugrel vs Clopidogrel for Stenting or Flow Diverter for Unruptured Aneurysm | Biotech Hunter | Biotech Hunter