Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

PHASE3RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

September 19, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

March 31, 2026

Conditions
AnesthesiaPropofol Adverse ReactionEtomidate Adverse ReactionAnesthesia ComplicationAnesthesia; Adverse EffectAnesthesia; Reaction
Interventions
DRUG

Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2)

"The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).~The objectives are to compare the treatment arms, P2E7 and P7E2, in a randomized controlled double-blind trial for anesthesia for endoscopic procedures. Comparison between an admixture of Propofol/Etomidate 75%/25% versus 25%/75% being utilized as principal anesthetic for endoscopic procedures at CUH endoscopy lab."

DRUG

Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)

"The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).~The objectives are to compare the treatment arms, P2E7 and P7E2, in a randomized controlled double-blind trial for anesthesia for endoscopic procedures. Comparison between an admixture of Propofol/Etomidate 75%/25% versus 25%/75% being utilized as principal anesthetic for endoscopic procedures at CUH endoscopy lab."

Trial Locations (1)

75390

RECRUITING

Clements University Hospital, Dallas

All Listed Sponsors
lead

University of Texas Southwestern Medical Center

OTHER