A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

PHASE1RecruitingINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

July 5, 2022

Primary Completion Date

March 28, 2027

Study Completion Date

September 28, 2028

Conditions
MelanomaNon-Small-Cell Lung CancerThyroid CancerGlioma
Interventions
DRUG

PF-07799933

Tablet

DRUG

binimetinib

Tablet

BIOLOGICAL

cetuximab

Injection for intravenous use

Trial Locations (40)

10021

RECRUITING

MSK David H. Koch Center for Cancer Care, New York

10022

RECRUITING

Memorial Sloan Kettering Cancer Center 53rd street, New York

10065

RECRUITING

Memorial Sloan Kettering Cancer Center, New York

33136

RECRUITING

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami

RECRUITING

University of Miami Sylvester Comprehensive Cancer Center-The Griffin Research Building, Miami

37203

RECRUITING

Sarah Cannon Research Institute - Pharmacy, Nashville

RECRUITING

SCRI Oncology Partners, Nashville

RECRUITING

TriStar Bone Marrow Transplant, Nashville

RECRUITING

TriStar Centennial Medical Center - Cell Processing Lab, Nashville

RECRUITING

TriStar Centennial Medical center, Nashville

44106

RECRUITING

Cleveland Clinic Taussig Cancer Center Investigational Pharmacy, Cleveland

44195

RECRUITING

Cleveland Clinic, Cleveland

48170

RECRUITING

CT Scan and Echo Only: Henry Ford Medical Center-Plymouth, Plymouth

48202

RECRUITING

Brigitte Harris Cancer Pavilion, Detroit

RECRUITING

Henry Ford Hospital, Detroit

48377

RECRUITING

Henry Ford Medical Center - Columbus, Novi

72703

RECRUITING

Highlands Oncology Group, Fayetteville

72758

RECRUITING

Highlands Oncology Group, Rogers

72762

RECRUITING

Highlands Oncology Group, Springdale

78229

RECRUITING

START San Antonio, San Antonio

80045

RECRUITING

Clinical and Translational Research Center (CTRC), Aurora

RECRUITING

UCHealth Sue Anschutz-Rodgers Eye Center, Aurora

RECRUITING

University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora

RECRUITING

University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP), Aurora

RECRUITING

University of Colorado Hospital - Anschutz Outpatient Pavilion (AOP), Aurora

97213

RECRUITING

Providence Cancer Institute Franz Clinic, Portland

RECRUITING

Providence Portland Medical Center, Portland

3109601

RECRUITING

Rambam Health Care Campus, Haifa

5265601

RECRUITING

Sheba Medical Center, Ramat Gan

6423906

NOT_YET_RECRUITING

Sourasky Medical Center, Tel Aviv

9112001

RECRUITING

Hadassah Medical Center, Jerusalem

02115

RECRUITING

Brigham and Women's Hospital, Boston

02215

RECRUITING

Dana-Farber Cancer Institute, Boston

02459

RECRUITING

DFCI Chestnut Hill, Newton

07748

RECRUITING

MSK Monmouth, Middletown

T6G 1Z2

NOT_YET_RECRUITING

Cross Cancer Institute, Edmonton

K1H 8L6

RECRUITING

The Ottawa Hospital - General Campus, Ottawa

M5G 2M9

RECRUITING

Princess Margaret Cancer Centre, Toronto

H3T 1E2

RECRUITING

Jewish General Hospital, Montreal

H4A 3J1

RECRUITING

McGill University Health Centre, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY