Genetic Determinants of the Coronary Microvascular Obstruction in PCI

CompletedOBSERVATIONAL
Enrollment

80

Participants

Timeline

Start Date

April 11, 2022

Primary Completion Date

March 5, 2023

Study Completion Date

March 25, 2023

Conditions
Myocardial InfarctionNo-Reflow Phenomenon
Interventions
GENETIC

different variants of SNPs that may be associated with the coronary microvascular obstruction development

Some variants of SNPs determine endothelial function, microcirculation, hemostasis, and inflammation in MI patients. They may be associated with the development of coronary microvascular obstruction during emergency PCI. A link between the different SNPs and the CMVO development will be established. SNP will be determined by real-time polymerase chain reaction with high-resolution melting curve analysis using TaqMan fluorescent probes.

Trial Locations (2)

603018

City Clinical Hospital No. 13 of the Avtozavodsky District of Nizhny Novgorod, Nizhny Novgorod

603104

Central Research Laboratory of the Privolzhsky Research Medical University, Nizhny Novgorod

All Listed Sponsors
lead

Privolzhsky Research Medical University

OTHER