70
Participants
Start Date
October 1, 2022
Primary Completion Date
January 31, 2024
Study Completion Date
January 31, 2024
Toothpaste with hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP)
"Subgingival instrumentation will be performed in two sessions, with a maximum interval of one week, with hand and automatic devices, under local anaesthesia. Full-mouth dental polishing (air-polishing) will be performed immediately after the second session, to eliminate any dental staining.~Experimental anti-staining toothpaste formulation (Dentaid, Barcelona, Spain) includes hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP), within its ingredients. Participants will use the test or control toothpaste three times daily with a manual toothbrush followed by the use, twice daily, of a 0.12% chlorhexidine, commercially available, mouth rinse."
Toothpaste without hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP)
"Subgingival instrumentation will be performed in two sessions, with a maximum interval of one week, with hand and automatic devices, under local anaesthesia. Full-mouth dental polishing (air-polishing) will be performed immediately after the second session, to eliminate any dental staining.~Experimental anti-staining toothpaste formulation without tripolyphosphate and polyvinylpyrrolidone (PVP), within its ingredients. Participants will use the test or control toothpaste three times daily with a manual toothbrush followed by the use, twice daily, of a 0.12% chlorhexidine, commercially available, mouth rinse."
Faculty of Dentistry, University Complutense of Madrid (UCM), Madrid
Dentaid SL
INDUSTRY
Universidad Complutense de Madrid
OTHER