NCT05353530View on ClinicalTrials.gov

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma

PHASE1RecruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

July 25, 2023

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2042

Conditions
Glioblastoma MultiformeGlioblastoma
Interventions
BIOLOGICAL

Ex-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells

Single dose of 8R-70CAR T cells administered IV

Trial Locations (1)

32608

RECRUITING

University of Florida Health, Gainesville

All Listed Sponsors
collaborator

AM Rosen Foundation

UNKNOWN

lead

University of Florida

OTHER