514
Participants
Start Date
June 17, 2022
Primary Completion Date
December 17, 2023
Study Completion Date
July 3, 2024
HLX14
"Subjects will receive a total of 3 doses of subcutaneous injection of HLX14 (once every 6 months (Q6M)).~Treatment period 1: D1-D364, subjects will receive subcutaneous injection of HLX14 60mg on D1 and D183.~Treatment period 2: D365-D546, on D365, subjects will be continue with a third dose of HLX14."
Prolia®
"Subjects will receive a total of 3 doses of subcutaneous injection of HLX14 or Prolia® (once every 6 months (Q6M)).~Treatment period 1: D1-D364, subjects will receive subcutaneous injection of Prolia® 60mg on D1 and D183.~Treatment period 2: D365-D546, on D365, subjects in the Prolia® arm will be re-randomized 1:1 to either continue with a third dose of Prolia® or transition to HLX14 and receive a single dose of HLX14."
The First Hospital of Hebei Medical University, Shijiazhuang
The Fourth Affiliated Hospital of Harbin Medical University, Harbin
Inner Mongolia Baogang hospital, Baotou
Huai'an First People's Hospital, Huai'an
The Second Affiliated Hospital of Nanjing Medical University, Nanjing
Affiliated Hospital of Xuzhou Medical University, Xuzhou
Ruian People's Hospital, Rui'an
People's Hospital of Ningxia Hui Autonomous Region, Yinchuan
Zhejiang Provincial People's Hospital, Hangzhou
Beijing BOAI Hospital, Beijing
Beijing Hospital, Beijing
Beijing Jishuitan Hospital, Beijing
BeiJing PINGGU Hospital, Beijing
The Third Xiangya Hospital of Central South University, Changsha
Changzhou NO.2 People's Hospital, Changzhou
West China Hospital of Sichuan University, Chengdu
Chongqing University three Gorges Hospital, Chongqing
The Second Affiliated Hospital of Chongqing Medical University, Chongqing
Department of Geriatrics, Guangzhou First People's Hospital, Guangzhou
Guangzhou First People's Hospital, Guangzhou
The First Affiliated Hospital of USTC Anhui Provincial Hospital, Hefei
Qilu Hospital of Shandong University, Jinan
Shandong Provincial Hospital, Jinan
Affiliated Hospital of Jining Medical University, Jining
The Third People's Hospital of Yunnan Province, Kunming
Henan Luoyang Orthopedic Hospital, Luoyang
The First Affiliated Hospital of Henan University of Science and Technology, Luoyang
Jiangxi Provincial People's Hospital, Nanchang
Nanchang Hongdu Hospital of traditional Chinese Medicine, Nanchang
Nanchang Third Hospital, Nanchang
Pingxiang Peoples's Hospital, Pingxiang
Suining Central Hospital, Suining
First Hospital of Shanxi Medical University, Taiyuan
Second hospital of Shanxi Medical University, Taiyuan
Tianjin First Central Hospital, Tianjin
Weifang People's Hospital, Weifang
Union Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology, Wuhan
Honghui Hospital,Xi'an Jiaotong University, Xi'an
Shanghai Henlius Biotech
INDUSTRY