Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis

RecruitingOBSERVATIONAL
Enrollment

550

Participants

Timeline

Start Date

February 6, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

March 31, 2027

Conditions
Late-Onset Neonatal SepsisExtreme PrematurityNeonatal Hypotension
Interventions
DRUG

Dopamine

Start at 5mics/kg/min, increase every 16-30 minutes by 5 mics/kg/min to a maximum dose of 15 mics/kg/min or adequate response.

DRUG

Norepinephrine

Start at 0.05 mics/kg/min, increase every 16-30 minutes by 0.05 mics/kg/min to maximum dose of 0.15/mics/kg/min or adequate response

Trial Locations (23)

28046

RECRUITING

La Paz University Hospital, Madrid

45404

RECRUITING

Dayton Children's Hospital, Dayton

78229

RECRUITING

Methodist Healthcare, San Antonio

85006

NOT_YET_RECRUITING

Banner-University Medical Center Phoenix, Phoenix

Unknown

RECRUITING

Foothill's Medical Centre, Calgary

RECRUITING

BC Women's Hospital, Vancouver

NOT_YET_RECRUITING

St.Boniface Hospital, Winnipeg

RECRUITING

Winnipeg Health Sciences Centre, Winnipeg

RECRUITING

IWK Health Centre, Halifax

RECRUITING

McMaster Children's Hospital, Hamilton

RECRUITING

London Health Sciences Centre, London

RECRUITING

Children's Hospital of Eastern Ontario, Ottawa

RECRUITING

Hospital for Sick Children, Toronto

RECRUITING

Mount Sinai Hospital, Toronto

RECRUITING

Sunnybrook Health Sciences Centre, Toronto

RECRUITING

Windsor Regional Hospital, Windsor

RECRUITING

CHU Sainte- Justine, Montreal

RECRUITING

Jewish General Hospital, Montreal

RECRUITING

Montreal Children's Hospital, Montreal

RECRUITING

University Cork College, Cork

NOT_YET_RECRUITING

Coombe Women & Infants University Hospital, Dublin

RECRUITING

Shamir Medical Center, Be’er Ya‘aqov

V8Z 6R5

RECRUITING

Victoria General Hospital, Victoria

All Listed Sponsors
collaborator

Sunnybrook Health Sciences Centre

OTHER

collaborator

The Hospital for Sick Children

OTHER

collaborator

London Health Sciences Centre

OTHER

collaborator

Windsor Regional Hospital

OTHER

collaborator

Foothills Medical Centre

OTHER

collaborator

Health Sciences Centre, Winnipeg, Manitoba

OTHER

collaborator

St. Boniface Hospital

OTHER

collaborator

Jewish General Hospital

OTHER

collaborator

St. Justine's Hospital

OTHER

collaborator

IWK Health Centre

OTHER

collaborator

University College Cork

OTHER

collaborator

Coombe Women and Infants University Hospital

OTHER

collaborator

Island Health, Victoria, BC

OTHER

collaborator

Assaf-Harofeh Medical Center

OTHER_GOV

collaborator

Dayton Children's Hospital

OTHER

collaborator

Banner University Medical Center

OTHER

collaborator

Methodist Healthcare

OTHER

collaborator

Hospital Universitario La Paz

OTHER

collaborator

McMaster Children's Hospital

OTHER

collaborator

Children's Hospital of Eastern Ontario

OTHER

collaborator

BC Women's Hospital & Health Centre

OTHER

collaborator

Stony Brook University

OTHER

collaborator

The Children's Hospital at Montefiore

OTHER

collaborator

Golisano Children's Hospital

UNKNOWN

lead

Mount Sinai Hospital, Canada

OTHER