Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia

NARecruitingINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

October 13, 2021

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2026

Conditions
SchizophreniaSchizo Affective Disorder
Interventions
DEVICE

Repetitive Transcranial Magnetic Stimulation (rTMS)

"rTMS is a technique of TMS that allows for selective external manipulation of neural activity in a non-invasive manner. During rTMS a rapidly changing current is passed through an insulated coil placed against the scalp. This generates a temporary magnetic field, which in turn induces electrical current in neurons and allows for modulation of neural circuitry.~The rTMS pulses will be delivered in a pattern consisting of 2 s trains of 3 pulses at 50 Hz, repeated at 5 Hz every 10s for 600 total pulses."

DEVICE

Sham Repetitive Transcranial Magnetic Stimulation (rTMS)

"rTMS is a technique of TMS that allows for selective external manipulation of neural activity in a non-invasive manner. During rTMS a rapidly changing current is passed through an insulated coil placed against the scalp. This generates a temporary magnetic field, which in turn induces electrical current in neurons and allows for modulation of neural circuitry.~The rTMS pulses will be delivered in a pattern consisting of 2 s trains of 3 pulses at 50 Hz, repeated at 5 Hz every 10s for 600 total pulses.~Sham is achieved by using a coil with a magnetic shield preventing magnetic field from reaching the head."

Trial Locations (1)

02478

RECRUITING

McLean Hospital, Belmont

All Listed Sponsors
collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Mclean Hospital

OTHER