Protective Effect of Thymosin Α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)

NARecruitingINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

July 1, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Acute Aortic SyndromeAortic Dissection Type a
Interventions
DRUG

Thymosin Alpha1, 28A-Glycine-28B-L-Arginine-28C-L-Glutamic Acid-28D-L-Alanine-28E-L-Proline-28F-L-Alanine-28G-L-Asparagine-

Thymosin alpha 1, 1.6mg injection hypodermic (I.H), every 12 hours for 5 days at least during the ICU admission. The administration will be terminated any day during the treatment when the patient is deemed as qualified for ICU discharge or dead.

DRUG

Blank control

Blank control

Trial Locations (15)

10029

RECRUITING

Beijing Anzhen Hospital Capital Medical University, Beijing

210029

RECRUITING

The First Affiliated Hospital of Nanjing Medical University, Nanjing

Unknown

RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

RECRUITING

Nanjing First Hospital Nanjing Medical University, Nanjing

RECRUITING

Subei People's Hospital of Jiangsu Province, Yangzhou

RECRUITING

Qilu Hospital of Shandong University, Jinan

RECRUITING

West China Hospital of Sichuan University, Chengdu

RECRUITING

The Friendship Hospital of Yili Kazak Autonomous Prefecture, Kazak

RECRUITING

The Seventh Affiliated Hospital of Xinjiang Medical University, Ürümqi

RECRUITING

The First Affiliated Hospital of Kunming Medical University, Kunming

RECRUITING

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou

RECRUITING

The Second Affiliated Hospital of Nanchang University, Nanchang

RECRUITING

Shanghai East Hospital Tongji University, Shanghai

RECRUITING

TEDA International Cardiovascular Hospital, Tianjin

Sponsors
All Listed Sponsors
collaborator

Beijing Anzhen Hospital

OTHER

collaborator

Second Affiliated Hospital of Nanchang University

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

The First Affiliated Hospital of Guangzhou Medical University

OTHER

collaborator

Northern Jiangsu People's Hospital

OTHER

collaborator

Guangdong Provincial People's Hospital

OTHER

collaborator

First Affiliated Hospital of Kunming Medical University

OTHER

collaborator

Nanjing First Hospital, Nanjing Medical University

OTHER

collaborator

Shanghai East Hospital,Tongji University School of Medicine

UNKNOWN

collaborator

The Seventh Affiliated Hospital of Xinjiang Medical University

UNKNOWN

collaborator

TEDA International Cardiovascular Hospital

OTHER

collaborator

The First Affiliated Hospital of Bengbu Medical University

OTHER

collaborator

West China Hospital

OTHER

lead

Nanjing Medical University

OTHER