Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using MR Guided Linear Accelerator

Enrolling by invitationOBSERVATIONAL
Enrollment

58

Participants

Timeline

Start Date

January 1, 2022

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2033

Conditions
Rectal Cancer
Interventions
RADIATION

Magnetic resonance guided radiotherapy

Radical radiotherapy boosting for low rectal cancer through magnetic resonance guided radiotherapy linear accelerator.

DRUG

Chemotherapy

"For patients with AJCC stage II and III and age \< 72 years old, Capox ×6→capecitabine×2.~Detailed usage: Oxaliplatin 130mg/m2 (reduced to 100mg/m2 during concurrent chemoradiotherapy), intravenous administration, d1. Capecitabine 1000mg / m2, twice a day, d1-14. Repeated every 3 weeks.~For patients aged ≥ 72 years, or the competent physician judges that the patients cannot tolerate dual drug combined chemotherapy, capecitabine ×8 courses.~For patients with AJCC stage I, capecitabine ×4 courses."

Trial Locations (1)

510060

Sun Yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER