Optimize the Effects of Repetitive Transcranial Magnetic Stimulation on Neuropathic Pain

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

December 1, 2022

Study Completion Date

December 31, 2022

Conditions
Neuropathic PainRepetitive Transcranial Magnetic Stimulation
Interventions
DEVICE

Repetitive transcranial magnetic stimulation

Magnetic stimulation was performed using a figure-eight coil connected to a Magstim Rapid2 system, All patients seat in a comfortable reclining chair and delivered pcTBS protocol using repetitive transcranial magnetic stimulation . The stimulation intensity was set to 80% of the resting motor threshold, which is measured as the minimal intensity of stimulation evoking an electromyographic response ≥50µV on the first dorsal interosseus muscle of the hand contralateral to the stimulated hemisphere in at least 5 out of 10 trials. For this measurement, a figure-of-eight coil is positioned over the hand motor hotspot and oriented perpendicular to the central sulcus (parallel to the hemispheric midline).

DEVICE

Repetitive transcranial magnetic stimulation

Magnetic stimulation was performed using a figure-eight coil connected to a Magstim Rapid2 system, All patients seat in a comfortable reclining chair and delivered 10HZ protocol using repetitive transcranial magnetic stimulation . The stimulation intensity was set to 80% of the resting motor threshold, which is measured as the minimal intensity of stimulation evoking an electromyographic response ≥50µV on the first dorsal interosseus muscle of the hand contralateral to the stimulated hemisphere in at least 5 out of 10 trials. For this measurement, a figure-of-eight coil is positioned over the hand motor hotspot and oriented perpendicular to the central sulcus (45° away from the hemispheric midline).

Trial Locations (1)

Unknown

The second affliated hospital of zhejiang university, Hangzhou

All Listed Sponsors
lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER