NCT05337618View on ClinicalTrials.gov

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

PHASE2RecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

December 16, 2022

Primary Completion Date

April 1, 2026

Study Completion Date

September 20, 2026

Conditions
Traumatic Brain Injury
Interventions
DIAGNOSTIC_TEST

Full-band Electrocorticography

Diagnosis of spreading depolarizations in continuous electrocorticography

COMBINATION_PRODUCT

Treatment Algorithm

Protocol for escalation and de-escalation of physiologic-targeted and pharmacologic therapies to treat and prevent spreading depolarizations

Trial Locations (1)

45267

RECRUITING

University of Cincinnati, Cincinnati

All Listed Sponsors
collaborator

University of New Mexico

OTHER

collaborator

University of Pennsylvania

OTHER

lead

University of Cincinnati

OTHER